08/07/2026
Let's talk about regenerative endodontics!
The American Association of Endodontists’ Glossary of Endodontic Terms defines regenerative endodontics as “biologically-based procedures designed to physiologically replace damaged tooth structures, including dentin and root structures, as well as cells of the pulp-dentin complex.”
In the case shown here we had a young patient with tooth #30 causing pain. Tooth #30 was officially diagnosed with pulpal necrosis with symptomatic apical periodontitis. A predictable outcome utilizing traditional non-surgical root canal treatment would be difficult given that the apices of the roots were immature and wide open. Regenerative endodontics was selected as an appropriate treatment option. The patient and parents were ideal for this case as they showed up to all treatment appointments and recommended follow up appointments to monitor the case.
During the initial visit access was made into the pulp chamber and the tooth was irrigated extensively with dilute irrigation solutions and then the canals were dried and calcium hydroxide was placed in the root canal system for 1 month.
During the second visit the tooth was irrigated extensively with 17% EDTA to open dentin tubules and release growth factors to help with intended root development. Bleeding was initiated from the periapical tissues until all canals were filled with blood. The goal of this step is to allow stem cells from the apical papilla to travel into the canals. The access was closed permanently with a collaplug over the blood filled canals followed by MTA, BC Liner, and a resin restoration.
At subsequent 6 month, 1 year and 2 year post-operative appointments all goals have been achieved:
Resolution of periapical infection✅
Resolution of symptoms ✅
Continued root development ✅
This patient and parents are pleased with the result, as are we! Hopefully no further treatment will be needed in the future, but if it is then non-surgical root canal treatment could be carried out predictably due to proper maturation of the root canal system.