22/04/2026
Metronidazolul este un antibiotic , eficient împotriva bacteriilor anaerobe(traiesc fara oxigen) si utilizat frecvent , in combinatie cu augmentinul , pentru : 📍 abcesele dentare cu puroi si tumefactie faciala infectii parodontale grave postextractional , pentru complicatii pericoronarita severa cu trismus (dificultatea de a deschide gura). Nu luati antibiotice pentru o simpla carie sau o durere , care cedeaza la antialgice , riscati sa dezvoltati rezistenta , iar la nevoie sa devina ineficiente ! Administrand antibioticul , fara consult si tratament stomatologic , infectia va reveni , adesea mai agresiva ! Medicatia adecvata tipului de infectie , este cea prescrisa de medicul tau stomatolog ! 📍 Bd. Dacia nr 5 , sc. B , parter ☎️ 0744 307288
Metronidazole in Dentistry ⬇️
🔹 Nitroimidazole antibiotic
🔹 Bactericidal: forms toxic metabolites that damage DNA
🔹 Active only against obligate anaerobes and some protozoa
🔹 No aerobic coverage
Dental uses
🔹 ANUG/ANUP = classic indication
🔹 With amoxicillin for aggressive/refractory periodontitis
🔹 Adjunct in severe odontogenic infections with anaerobic component
Adverse effects
🔹 Disulfiram-like reaction with alcohol
🔹 Avoid alcohol during treatment and for 3 days after
🔹 Metallic taste
🔹 GI upset
🔹 Dark urine may occur
Drug interactions
🔹 Warfarin → ↑ INR / bleeding risk
🔹 Lithium → toxicity risk
Precautions
🔹 Use caution in liver disease
🔹 Traditionally avoided in 1st trimester pregnancy
High-yield pearl
🔹 Metronidazole = anaerobes only
🔹 Alcohol + metronidazole = severe reaction
