Pangan Dental Clinic

28/04/2026

No clinic on
May 1&2, 2026

Clinic will resume on May 4,2026

08/04/2026

No clinic on
April 13&14,2026

Clinic will resume on April 15,2026
10-4pm

31/03/2026

Pangan Dental Clinic will be close on

April 2, 2026- Maundy Thursday
April 3,2026- Good Friday

It will open on

April 4,2026
11:00-5:00pm

27/02/2026

Pangan Dental Clinic

There will be no clinic on

March 2-6, 2026
Clinic will resume on
March 7, 2026
11-5pm

24/12/2025

Pangan Dental Clinic

Clinic will be closed from
December 24-25, 2025
and
December 31- January 1,2026

Merry Christmas 🎄 🎄🎄

21/10/2025

Pangan Dental Clinic
ADVISORY

The clinic will be closed on the following days:
• Oct. 22 to 27, 2025
• Oct. 30 to Nov. 4, 2025
• Dec. 1 to 6, 2025

Thank you.

12/10/2025

Wisdom teeth, long considered disposable, are actually a rich source of mesenchymal stem cells capable of regenerating bone, muscle, nerve, and other vital tissues. These cells could one day play a key role in treating serious diseases, from arthritis and diabetes to cognitive disorders like Alzheimer’s and Parkinson’s. Harvesting them during routine tooth extractions is non-invasive and painless, making dental stem cells an accessible and promising option for regenerative medicine.

Clinics and companies now offer cryopreservation services to store stem cells from wisdom teeth, keeping them viable for decades. This biological “insurance” could be tapped for future treatments as research progresses in areas like autoimmune disease, spinal injuries, and corneal repair. What was once medical waste may soon become a powerful tool in modern medicine, unlocking therapies that conventional treatments cannot provide.

Sources/Credit:
Journal of Natural Science, Biology and Medicine. “Current overview on dental stem cells applications in regenerative dentistry.”
Stem Save (2025). Current Clinical Applications for Stem Cells.

12/07/2025

Emerging research has revealed an unexpected link between Alzheimer’s disease and oral health—specifically gum disease.
Scientists have discovered Porphyromonas gingivalis—the bacteria responsible for chronic periodontitis—inside the brain tissue of people who died with Alzheimer’s. When researchers introduced this bacteria into mice, it not only spread to their brains but also triggered the production of amyloid beta, the protein strongly tied to the onset of Alzheimer’s.

Even more striking, researchers detected toxic enzymes from these bacteria in individuals showing early brain changes associated with Alzheimer’s—years before any dementia symptoms appeared. This suggests that such infections could quietly establish themselves long before the disease becomes obvious.

These findings lend weight to the theory that, in some cases, Alzheimer’s may have an infectious component rather than being solely a neurodegenerative condition. In response to this, the biotech company Cortexyme has developed an experimental drug, COR388, which has shown early promise in animal studies—reducing both bacterial presence and amyloid beta accumulation. Human trials are still needed to determine whether this approach will translate to effective treatment.

While experts caution that more research is required, they emphasize the importance of these discoveries—especially since there have been no major breakthroughs in Alzheimer’s treatment for over 15 years. One clear takeaway: good oral hygiene might play a bigger role in protecting our brains than we ever realized. Brushing, flossing, and regular dental checkups could prove to be simple yet powerful tools for long-term brain health.

04/07/2025

Most people brush their teeth for fresh breath or a clean smile. But a groundbreaking study has revealed a deeper, life-saving impact. In a large-scale analysis of 1,583 hospitalized adults, researchers found that brushing your teeth at night can significantly reduce the risk of cardiovascular events and even early death. Those who brushed only in the morning or skipped brushing altogether were far more likely to experience heart complications compared to those who brushed before bed.

Brushing at night is more than a dental habit. It actively prevents the buildup of harmful oral bacteria that trigger systemic inflammation, a known driver of cardiovascular disease. The numbers speak clearly. Individuals who brushed only before bed had a hazard ratio of about 0.55 to 0.59 for cardiovascular risk. The study also showed that smoking made outcomes worse, especially in those who neglected nighttime brushing. The connection between oral hygiene and heart health is no longer a theory, it is now evidence-based science.

The takeaway is simple but powerful. Brushing your teeth before bed is not just about cleanliness, it is a heart-protective act backed by clinical research. Your toothbrush might be the smallest tool in your bathroom but it carries the weight of your long-term health. Do not skip this nightly ritual. It could be the easiest step you take toward preventing heart disease and protecting your life

19/06/2025

👄 Recent research has increasingly supported the hypothesis that Alzheimer's disease may be linked to infection, particularly from bacteria in the mouth.

A study led by Jan Potempa found the gum disease-causing bacterium Porphyromonas gingivalis in the brains of deceased Alzheimer's patients. Experiments in mice showed that oral infection with P. gingivalis led to brain colonization by the bacteria and increased production of amyloid beta, a protein closely associated with Alzheimer's.

The researchers also discovered toxic enzymes called gingipains, produced by these bacteria, in the brains of both Alzheimer's patients and individuals without dementia, suggesting infection may occur before cognitive symptoms arise. While this does not definitively prove that gum disease causes Alzheimer's, it provides strong evidence of a connection and points to oral health as a potential factor in the disease's development.

New drugs targeting these bacterial toxins have shown promise in animal studies, but further research is needed to confirm these findings in humans

Follow Science Sphere for regular scientific updates 🧪

RESEARCH PAPER 📄

Stephen S. Dominy, “Porphyromonas gingivalis in Alzheimer’s disease brains: Evidence for disease causation and treatment with small-molecule inhibitors”, Science Advances. (2019).

13/05/2025