18/05/2026
Scientists have discovered that Porphyromonas gingivalis — a major bacterium involved in gum disease — has been detected in the brains of some patients with Alzheimer’s disease.
Researchers believe toxins released by these bacteria may contribute to inflammation and protein changes linked to neurodegeneration. The study does not prove that gum disease causes Alzheimer’s, but it adds to growing evidence that oral health and brain health may be closely connected.
Inflamed or bleeding gums may allow harmful bacteria and inflammatory molecules to enter the bloodstream and potentially affect other organs over time.
Healthy gums are about more than protecting teeth. They may also play a role in long-term systemic health.
📚 DOI: 10.1126/sciadv.aau3333
Dominy SS, et al. Porphyromonas gingivalis in Alzheimer's disease brains: Evidence for disease causation and treatment with small-molecule inhibitors. Sci Adv. 2019
