26/04/2026
As you age, your blood-brain barrier weakens, letting in harmful chemicals that cause inflammation. This weakening is associated with increased activity of TNAP (tissue-nonspecific alkaline phosphatase), but new research indicates that exercise can cause the liver to release the GPLD1 enzyme, which cleaves the tail of TNAP, leading to repair of the weak spots and protection of the brain from dementia. https://www.sciencedaily.com/releases/2026/02/260219040752.htm
