04/12/2025
Next-Generation Biomaterials and Digital Innovations for Maxillofacial Reconstruction and Regeneration
Dear Colleagues,
Advances in maxillofacial biomaterials and digital technologies are rapidly transforming clinical practice in oral and maxillofacial surgery. This Special Issue focuses on the new generation of materials, biologics, and technology-integrated solutions that are reshaping reconstruction, regeneration, and functional rehabilitation in the craniofacial region. The goal is to highlight breakthroughs that enhance predictability, safety, and long-term outcomes in both hard and soft tissue management.
This issue encompasses innovations across a wide spectrum of applications, including but not limited to, the following:
Next-generation materials for maxillofacial reconstruction;
Implantable devices optimized for craniofacial bone biology;
Biologic approaches and growth factor–integrated systems;
Soft-tissue fillers designed specifically for facial esthetics and functional restoration;
Digital navigation systems and augmented-reality–assisted surgical workflows;
Robotics and automation in maxillofacial surgery;
Nanotechnology-based enhancements for osseointegration and wound healing;
Smart materials incorporating sensors, controlled-release systems, or bio-responsive behaviors.
By bringing together research articles, reviews, and case-based studies, this Special Issue aims to provide a comprehensive overview of current trends and future directions. The intent is to inspire the development of clinically meaningful solutions that push the boundaries of maxillofacial innovation, improve treatment efficiency, and elevate patient-centered outcomes.
This Special Issue serves as a platform for scientists, clinicians, and engineers to exchange insights and expand interdisciplinary collaboration. By consolidating emerging evidence and technological progress, it seeks to stimulate further research and encourage the integration of advanced materials and digital tools into everyday clinical practice.
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